Rex Carlton is an unhappy IT worker in Buffalo, New York. His girlfriend left him and he hates his job. By chance, he sees an ad for a bike messenger and applies. He quits IT and awkwardly finds his way as a courier.
Meanwhile, the vampire coven in Buffalo is under attack by one of their own. After delivering a package Rex finds himself at the center of the vampire world.
Rex tries to navigate the streets and find love but may end up dead before it's all over.